Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: Epidemiology and Risk Factors
نویسندگان
چکیده
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe mucocutaneous responses caused by drugs that characterized widespread necrosis detachment. It is essential to know the risk factors those agents involved in development of this pathology order use them with caution susceptible patients have a high index suspicion.
منابع مشابه
Toxic epidermal necrolysis and Stevens-Johnson syndrome
Three cases are described in which Stevens-Johnson syndrome progressed in the course of a few days to toxic epidermal necrolysis. Trimethoprim-sulfamethoxazole, allopurinol in combination with hydrochlorothiazide, phenytoin and possibly ampicillin were implicated in the causation of the disease.
متن کاملToxic Epidermal Necrolysis and Stevens-Johnson Syndrome
The term toxic epidermal necrolysis (TEN) was introduced in 1956 by Lyell to describe four patients with a syndrome featured by extensive epidermal detachment with mucous membrane involvement, leaving the skin surface looking scalded. Necrolysis denotes necrosis and full thickness detachment of the epidermis. Toxic means severe constitutional symptoms and complications. Stevens-Johnson syndrome...
متن کامل[Stevens-Johnson syndrome/toxic epidermal necrolysis].
Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) is a severe skin reaction most often triggered by particular medications. Although Stevens-Johnson syndrome and toxic epidermal necrolysis were once thought to be separate conditions, they are now considered part of a continuum. Stevens-Johnson syndrome represents the less severe end of the disease spectrum, and toxic epidermal necro...
متن کاملCauses and treatments of Stevens - Johnson syndrome and toxic epidermal necrolysis in Iranian patients
Aims: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are serious severe cutaneous adverse reactions with high mortality and morbidity induced by medications. In this cross sectional study, we investigated, suspected drugs, and potential treatments of SJS/TEN. Methods: A cross- sectional descriptive study was conducted on 60 patients admitted with a diagnosis of Stevens-Jo...
متن کاملToxic epidermal necrolysis and Stevens-Johnson syndrome: a review.
OBJECTIVES The aims of this review are to summarize the definitions, causes, and clinical course as well as the current understanding of the genetic background, mechanism of disease, and therapy of toxic epidermal necrolysis and Stevens-Johnson syndrome. DATA SOURCES PubMed was searched using the terms toxic epidermal necrolysis, Stevens-Johnson syndrome, drug toxicity, drug interaction, and ...
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ژورنال
عنوان ژورنال: International journal of medical science and clinical research studies
سال: 2023
ISSN: ['2767-8326', '2767-8342']
DOI: https://doi.org/10.47191/ijmscrs/v3-i1-08